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Anticipating Disruption

Open Dialogue about Perimenopause with Dr. Amber Hull and Ally Iseman

Thank you to Ally | Modern Love Insights for inviting me to her monthly Open Dialogue and to you, the Substack community, who tuned in for the LIVE! In this video, we cover the mood swings commonly associated with the menstrual cycle (follicular, ovulatory and luteal). Ally shares some of her experience with the more insidious symptoms of perimenopause and how her partner showed up to support her. Then, I do a Show-and-Tell of products commonly prescribed in my clinical practice. Whether you’re experiencing hormonal shifts yourself or holding a partner through the experience, we hope you find these insights helpful.

Disclosure: Substack’s default AI tool has edited the length of the recording and smoothed the audio.


This month, I’m doing a collaboration about immigration with BC-based internist Dr. Robert Beck of The Interesting MD Podcast. This will be one of the most personal interviews I’ve done to date about my move to Canada. I’ll pass it along when it airs. I’ll also be talking with Josh Woll of The Sober Creative later this month about mind-body medicine and the health benefits of choosing an alcohol-free lifestyle. If you’re doing Dry January, I’m sending out love and solidarity!

I am continuing my cultural insubordination by providing you with 100% organic writing and artwork at a pace that’s personally sustainable for me. I do NOT use AI for idea generation, writing, editing or artwork. I will disclose if/when that changes. Every single word you read in these letters is mine. Every photo you see was taken with my gaze. I’ve turned down several product sponsorships in 2025 in order to stay true to my own voice and keep my letters free of sales pitches. I want you to see my name in your inbox and get excited about my creativity. Not marketing emails or derivative slop. If you value this work, I invite you to buy me a coffee or contribute at any level that feels good to you.


Wherever you are in the world, I invite you to consider how AI is being used non-consensually and the effects it’s having on the human mind. Please talk with your lawmakers about the humane use of technology- including reasonable guardrails, corporate accountability, compensation for intellectual property and age-restrictions. This technology is advancing more quickly than we can interrupt it turning into malignancy; that needs to change. I strongly recommend following Joseph Gordon-Levitt for practical information on what you can do to advocate and use AI mindfully.

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AI companies are robbing everyone
California AB-412 would force AI companies to be transparent about what data they’ve taken to build their models. California State Legislature: please pass this bill. And for everyone else, sign the petition here. 🔴…
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Wishing you a healthy and joyful 2026!

All my Best,

Amber Hull, DO

Under the White Coat is a 100% Organic expression of Human Intelligence. To receive new posts and support my work, consider becoming a free or paid subscriber.

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